p53 polymorphism and risk of cervical cancer

Agnetha M. Josefsson, Patrik K. E. Magnusson, Nathalie Ylitalo, Pernilla Quarforth-Tubbin, Jan Pontén, Hans Olov Adami and Ulf B. Gyllensten ()
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Agnetha M. Josefsson: Unit of Medical Genetics, Biomedical Centre, University of Uppsala
Patrik K. E. Magnusson: Unit of Medical Genetics, Biomedical Centre, University of Uppsala
Nathalie Ylitalo: Karolinska Institutet
Pernilla Quarforth-Tubbin: Unit of Medical Genetics, Biomedical Centre, University of Uppsala
Jan Pontén: Unit of Medical Genetics, Biomedical Centre, University of Uppsala
Hans Olov Adami: Karolinska Institutet
Ulf B. Gyllensten: Unit of Medical Genetics, Biomedical Centre, University of Uppsala

Nature, 1998, vol. 396, issue 6711, 531-531

Abstract: Abstract Storey and co-workers 1 claim that there is an association between a common variant of the p53 tumour-suppressor gene and the development of invasive cervical carcinoma. Here we present evidence to refute this, based on a reassessment of the importance of the polymorphism at codon 72 in the p53 gene for the development of cervical cancer.

Date: 1998
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DOI: 10.1038/25037

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