Translational control perks up

Robert H. Silverman () and Bryan R. G. Williams ()
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Robert H. Silverman: The Cleveland Clinic Foundation
Bryan R. G. Williams: The Cleveland Clinic Foundation

Nature, 1999, vol. 397, issue 6716, 209-211

Abstract: A cell's response to stress is often linked to protein synthesis and folding. These responses must have been conserved through evolution — otherwise, how would multicellular organisms ever have arisen? An evolutionary link has now been found in the form of a newly cloned mammalian stress-response protein called PERK. This protein has features of two gene products that are involved in the stress response in yeast.

Date: 1999
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DOI: 10.1038/16586

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