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Capping off the ends

Carolyn Price ()
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Carolyn Price: N146 Beadle Center, University of Nebraska

Nature, 1999, vol. 397, issue 6716, 213-214

Abstract: Telomeres, the ends of chromosomes, present cells with a problem -- they can trigger DNA-damage responses and may become degraded or fuse with one another. To prevent this, telomeres are complexed with proteins. One such protein -- the Oxytricha telomere end-binding protein -- has now been crystallized, and the structure shows how it is exquisitely tailored for its job.

Date: 1999
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DOI: 10.1038/16598

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