Sugars slide into heparin activity

Pierre Sinaÿ ()
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Pierre Sinaÿ: the Departement de Chimie, Ecole Normale Suprieure

Nature, 1999, vol. 398, issue 6726, 377-378

Abstract: The first synthetic carbohydrates have been created with heparin-like ability to inhibit thrombin and prevent blood coagulation. Not only is this a stunning achievement in terms of organic synthesis, but the synthetic version may offer fewer side effects compared with natural heparin.

Date: 1999
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DOI: 10.1038/18783

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