Virus on virus infects bacterium

Ronald K. Taylor ()
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Ronald K. Taylor: Dartmouth Medical School

Nature, 1999, vol. 399, issue 6734, 312-313

Abstract: The bacterium that causes cholera,Vibrio cholerae, does not encode the cholera toxin itself. The toxin is encoded by a virus (known as a bacteriophage), which infects the V. choleraethrough a bacterial structure called the toxin co-regulated pilus. It now turns out that this pilus is itself encoded by yet another bacteriophage. So, only when the bacterium has acquired both phages will it have its full complement of virulence genes.

Date: 1999
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DOI: 10.1038/20565

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