Bonsai flies

Alison Mitchell

Nature, 1999, vol. 400, issue 6740, 115-115

Abstract: If fruitflies are reared without proper nutrition they end up half the normal size. Mutations in a gene calledchicohave now been found to give the same effect. The vertebrate homologues of the Chico protein turn out to be members of the insulin-receptor substrate family, and it is thought that Chico may be part of a nutritional-sensing system that regulates cell growth in response to nutritional conditions.

Date: 1999
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DOI: 10.1038/22003

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