Antibody clears senile plaques

Peter H. St George-Hyslop () and David A. Westaway
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Peter H. St George-Hyslop: Centre for Research in Neurodegenerative Diseases, University of Toronto
David A. Westaway: Centre for Research in Neurodegenerative Diseases, University of Toronto

Nature, 1999, vol. 400, issue 6740, 116-117

Abstract: One characteristic of Alzheimer's disease is the deposition of extracellular plaques of the amyloid-β peptide (Aβ). By immunizing a mouse model of Alzheimer's disease with Aβ, deposition of these plaques can be blocked. Although the mechanism is not known, this could be a first step towards a vaccine for Alzheimer's disease.

Date: 1999
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DOI: 10.1038/22006

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