All's well that ends dead
Timothy S. Zheng () and
Richard A. Flavell ()
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Timothy S. Zheng: Biogen Inc.
Richard A. Flavell: Section of Immmunobiology, Yale University School of Medicine, and the Howard Hughes Medical Institute
Nature, 1999, vol. 400, issue 6743, 410-411
Abstract:
When under attack from pathogens, the body expands its population of lymphoid cells. Once the pathogen has been destroyed, the excess cells must be eliminated, and this is done by cell suicide (apoptosis). People with a disease called type II ALPS cannot efficiently destroy the extra lymphoid cells, and it turns out that this is because they have mutations in a protein at the heart of apoptosis, caspase-10.
Date: 1999
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:400:y:1999:i:6743:d:10.1038_22659
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DOI: 10.1038/22659
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