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Oscillations in the basal ganglia

Thomas Wichmann () and Mahlon R. DeLong
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Thomas Wichmann: Emory University
Mahlon R. DeLong: Emory University

Nature, 1999, vol. 400, issue 6745, 621-622

Abstract: Neurons within the basal ganglia — a network of brain structures that may influence information processing in the cortex — can fire in oscillatory bursts. A new study sheds light on the origin of these bursts by defining synchronized oscillations in a cell-culture model of the basal ganglia. Interestingly, this 'pacemaker' seems to oscillate at roughly the same frequency as the tremors seen in people with Parkinson's disease.

Date: 1999
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DOI: 10.1038/23148

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