Rhapsody in G proteins

Johannes L. Bos () and Fried J. T. Zwartkruis
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Johannes L. Bos: Laboratory for Physiological Chemistry, Utrecht University
Fried J. T. Zwartkruis: Laboratory for Physiological Chemistry, Utrecht University

Nature, 1999, vol. 400, issue 6747, 820-821

Abstract: Guanine-nucleotide-binding proteins are molecular switches that transduce the signals received at a cell's surface to elicit a biological response from the proteins inside. There are two types of G protein — the heterotrimeric G proteins and the small GTPases. New research shows that a well-known small GTPase called Rap1 is regulated by a heterotrimeric G protein, via a GTPase-activating protein called Rap1GAPII.

Date: 1999
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DOI: 10.1038/23594

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