Where do the electrons go?

Rudi Glockshuber ()
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Rudi Glockshuber: Institut für Molekularbiologie und Biophysik, Eidgenössische Technische Hochschule

Nature, 1999, vol. 401, issue 6748, 30-31

Abstract: When a newly synthesized protein folds into the correct three-dimensional conformation, bonds between the thiol groups of cysteine residues - so-called disulphide bonds - cannot form spontaneously. This is because bond formation generates two electrons, which need to be mopped up by an oxidant. Studies in bacteria have identified two members of the electron-transport chain as oxidants that can do this job.

Date: 1999
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DOI: 10.1038/43344

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