Condensed matter in cell death

Naoufal Zamzami and Guido Kroemer ()
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Naoufal Zamzami: the Apoptosis, Cancer and Immunity Laboratory associated with the National League against Cancer, CNRS-ERS1984
Guido Kroemer: the Apoptosis, Cancer and Immunity Laboratory associated with the National League against Cancer, CNRS-ERS1984

Nature, 1999, vol. 401, issue 6749, 127-128

Abstract: During programmed cell death (apoptosis), the doomed cell shrinks and is engulfed by its neighbours. Part of this process involves destruction of the nucleus. A factor involved in nuclear destruction has now been identified. Known as Acinus, it adds an extra level of complexity to what we know about digestion of nuclear DNA, because it seems to act without a DNA-digesting (DNase) activity.

Date: 1999
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DOI: 10.1038/43591

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