Global methylation in eutherian hybrids

Irmgard Roemer, Frank Grützner, Heinz Winking, Thomas Haaf, Annie Orth, Lulu Skidmore, Doug Antczak and Reinald Fundele ()
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Irmgard Roemer: Max-Planck-Institut für Molekulare Genetik
Frank Grützner: Max-Planck-Institut für Molekulare Genetik
Heinz Winking: Institut für Biologie, Medizinische Universität Lübeck
Thomas Haaf: Max-Planck-Institut für Molekulare Genetik
Annie Orth: Laboratoire Génome et Populations, Université de Montpellier II
Lulu Skidmore: Camel Reproduction Centre
Doug Antczak: James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University
Reinald Fundele: Max-Planck-Institut für Molekulare Genetik

Nature, 1999, vol. 401, issue 6749, 131-132

Abstract: Abstract O'Neill et al. propose that epigenetic pro-cesses help to drive karyotypic evolution in marsupials1. Here we present evidence that global methylation patterns do not undergo dramatic changes in interspecific hybrids among three orders of placental mammals, indicating that the mechanisms underlying genome evolution may be different in placental mammals and marsupials.

Date: 1999
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DOI: 10.1038/43607

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