reply: Global methylation in eutherian hybrids

Rachel J. Waugh O'Neill (), Michael J. O'Neill and Jennifer A. Marshall Graves
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Rachel J. Waugh O'Neill: University of Connecticut
Michael J. O'Neill: University of Connecticut
Jennifer A. Marshall Graves: Department of Genetics and Human Variation La Trobe University

Nature, 1999, vol. 401, issue 6749, 132-132

Abstract: Abstract The absence of global methylation changes in eutherian interspecific hybrids compared with their parents, observed by Roemer et al., sharply contrasts with our own studies of interspecific hybrids between various species of kangaroo. We observed hybrid-specific undermethylation, retroelement activation and genome remodelling1, and suggested that these events occurring together may bring about rapid karyotypic change.

Date: 1999
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DOI: 10.1038/43611

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