Straight from the top

Earl K. Miller ()
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Earl K. Miller: Massachusetts Institute of Technology

Nature, 1999, vol. 401, issue 6754, 650-651

Abstract: The way we see the world around us depends on an interplay between two types of signal in the brain -- 'bottom-up' signals, which are derived from the physical data that bombard our sensory receptors, and 'top-down' signals, which interpret these data. For the first time, using a new surgical technique, we can directly see top-down signals in the brain, providing evidence that these signals come from the prefrontal cortex.

Date: 1999
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DOI: 10.1038/44291

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