See a pocket, block it

John P. Moore () and Tatjana Dragic
Additional contact information
John P. Moore: the Aaron Diamond AIDS Research Center, The Rockefeller University
Tatjana Dragic: the Aaron Diamond AIDS Research Center, The Rockefeller University

Nature, 1999, vol. 401, issue 6755, 759-759

Abstract: The focus of drugs for treating HIV-1 infection has switched from protease and reverse-transcriptase inhibitors to compounds that prevent fusion of the virus with human cells. The target protein in this pathway is known as gp41, and, last year, a pocket was identified in gp41 that could act as the binding site for a fusion inhibitor. Peptide inhibitors that specifically bind this pocket have now been identified.

Date: 1999
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/44504 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:401:y:1999:i:6755:d:10.1038_44504

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/44504

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().