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Policing rogue genes

Rueyling Lin () and Leon Avery ()
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Rueyling Lin: University of Texas Southwestern Medical Center
Leon Avery: University of Texas Southwestern Medical Center

Nature, 1999, vol. 402, issue 6758, 128-129

Abstract: Transposons are mobile chunks of DNA that insert themselves at random in the genome. This is dangerous, particularly in germline DNA (which is passed on to offspring). A new mechanism for suppressing transposon activity in the nematode worm Caenorhabditis elegans is proposed, and it involves the until-now mysterious phenomenon of RNA interference.

Date: 1999
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DOI: 10.1038/45938

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