Distorting sex ratios

Keith R. Willison ()
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Keith R. Willison: the Institute of Cancer Research, Chester Beatty Laboratories

Nature, 1999, vol. 402, issue 6758, 131-132

Abstract: During the production of sperm, there is a 50:50 chance that any sperm will contain either copy of a chromosome pair. But there are exceptions. One is the so-called mouse t-haplotype, an unusual variant of chromosome 17 that can be inherited in up to 99% of cases. The molecular basis of such skewed inheritance ratios is starting to be unravelled with the identification of a protein central to the process.

Date: 1999
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DOI: 10.1038/45943

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