Dual control of mitotic exit

Susanne Prinz and Angelika Amon ()
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Susanne Prinz: the Center for Cancer Research, Massachusetts Institute of Technology
Angelika Amon: the Center for Cancer Research, Massachusetts Institute of Technology

Nature, 1999, vol. 402, issue 6758, 133-135

Abstract: The cell cycle consists of four phases: S phase (in which genetic material is duplicated); mitosis (during which it is segregated between two daughter cells); and two 'rest' phases, G1 and G2. The transition between mitosis and G1 needs to be precisely timed, and one of the molecular steps involved in controlling this transition has now been pinned down to a protein known as Cdc20.

Date: 1999
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DOI: 10.1038/45949

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