Derailed axons get on track

Kai Zinn () and Aloisia Schmid ()
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Kai Zinn: California Institute of Technology
Aloisia Schmid: California Institute of Technology

Nature, 1999, vol. 402, issue 6761, 475-476

Abstract: How do growing axons in the central nervous system navigate through the jungle of cells that they encounteren routeto their targets? They are influenced by attractive and repulsive factors. One such factor, known as Derailed, is now shown to cause axon growth cones to head towards the so-called anterior commissure. It does so by repelling those axons that contain it from the posterior commissure.

Date: 1999
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DOI: 10.1038/44981

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