The DNA sequence of human chromosome 22

Dunham, I.; Hunt, A. R.; Collins, J. E.; Bruskiewich, R.; Beare, D. M.; Clamp, M.; Smink, L. J.; Ainscough, R.; Almeida, J. P.; Babbage, A.; Bagguley, C.; Bailey, J.; Barlow, K.; Bates, K. N.; Beasley, O.; Bird, C. P.; Blakey, S.; Bridgeman, A. M.; Buck, D.; Burgess, J.; Burrill, W. D.; Burton, J.; Carder, C.; Carter, N. P.; Chen, Y.; Clark, G.; Clegg, S. M.; Cobley, V.; Cole, C. G.; Collier, R. E.; Connor, R. E.; Conroy, D.; Corby, N.; Coville, G. J.; Cox, A. V.; Davis, J.; Dawson, E.; Dhami, P. D.; Dockree, C.; Dodsworth, S. J.; Durbin, R. M.; Ellington, A.; Evans, K. L.; Fey, J. M.; Fleming, K.; French, L.; Garner, A. A.; Gilbert, J. G. R.; Goward, M. E.; Grafham, D.; Griffiths, M. N.; Hall, C.; Hall, R.; Hall-Tamlyn, G.; Heathcott, R. W.; Ho, S.; Holmes, S.; Hunt, S. E.; Jones, M. C.; Kershaw, J.; Kimberley, A.; King, A.; Laird, G. K.; Langford, C. F.; Leversha, M. A.; Lloyd, C.; Lloyd, D. M.; Martyn, I. D.; Mashreghi-Mohammadi, M.; Matthews, L.; McCann, O. T.; McClay, J.; McLaren, S.; McMurray, A. A.; Milne, S. A.; Mortimore, B. J.; Odell, C. N.; Pavitt, R.; Pearce, A. V.; Pearson, D.; Phillimore, B. J.; Phillips, S. H.; Plumb, R. W.; Ramsay, H.; Ramsey, Y.; Rogers, L.; Ross, M. T.; Scott, C. E.; Sehra, H. K.; Skuce, C. D.; Smalley, S.; Smith, M. L.; Soderlund, C.; Spragon, L.; Steward, C. A.; Sulston, J. E.; Swann, R. M.; Vaudin, M.; Wall, M.; Wallis, J. M.; Whiteley, M. N.; Willey, D.; Williams, L.; Williams, S.; Williamson, H.; Wilmer, T. E.; Wilming, L.; Wright, C. L.; Hubbard, T.; Bentley, D. R.; Beck, S.; Rogers, J.; Shimizu, N.; Minoshima, S.; Kawasaki, K.; Sasaki, T.; Asakawa, S.; Kudoh, J.; Shintani, A.; Shibuya, K.; Yoshizaki, Y.; Aoki, N.; Mitsuyama, S.; Roe, B. A.; Chen, F.; Chu, L.; Crabtree, J.; Deschamps, S.; Do, A.; Do, T.; Dorman, A.; Fang, F.; Fu, Y.; Hu, P.; Hua, A.; Kenton, S.; Lai, H.; Lao, H. I.; Lewis, J.; Lewis, S.; Lin, S.-P.; Loh, P.; Malaj, E.; Nguyen, Thanh; Pan, H.; Phan, S.; Qi, S.; Qian, Y.; Ray, L.; Ren, Q.; Shaull, S.; Sloan, D.; Song, L.; Wang, Q.; Wang, Y.; Wang, Z.; White, J.; Willingham, D.; Wu, H.; Yao, Z.; Zhan, M.; Zhang, G.; Chissoe, S.; Murray, J.; Miller, N.; Minx, P.; Fulton, R.; Johnson, D.; Bemis, G.; Bentley, D.; Bradshaw, H.; Bourne, S.; Cordes, M.; Du, Z.; Fulton, L.; Goela, D.; Graves, T.; Hawkins, J.; Hinds, K.; Kemp, K.; Latreille, P.; Layman, D.; Ozersky, P.; Rohlfing, T.; Scheet, P.; Walker, C.; Wamsley, A.; Wohldmann, P.; Pepin, K.; Nelson, J.; Korf, I.; Bedell, J. A.; Hillier, L.; Mardis, E.; Waterston, R.; Wilson, R.; Emanuel, B. S.; Shaikh, T.; Kurahashi, H.; Saitta, S.; Budarf, M. L.; McDermid, H. E.; Johnson, A.; Wong, A. C. C.; Morrow, B. E.; Edelmann, L.; Kim, U. J.; Shizuya, H.; Simon, M. I.; Dumanski, J. P.; Peyrard, M.; Kedra, D.; Seroussi, E.; Fransson, I.; Tapia, I.; Bruder, C. E.; O'Brien, K. P.

The DNA sequence of human chromosome 22

I. Dunham (id1@sanger.ac.uk), A. R. Hunt, J. E. Collins, R. Bruskiewich, D. M. Beare, M. Clamp, L. J. Smink, R. Ainscough, J. P. Almeida, A. Babbage, C. Bagguley, J. Bailey, K. Barlow, K. N. Bates, O. Beasley, C. P. Bird, S. Blakey, A. M. Bridgeman, D. Buck, J. Burgess, W. D. Burrill, J. Burton, C. Carder, N. P. Carter, Y. Chen, G. Clark, S. M. Clegg, V. Cobley, C. G. Cole, R. E. Collier, R. E. Connor, D. Conroy, N. Corby, G. J. Coville, A. V. Cox, J. Davis, E. Dawson, P. D. Dhami, C. Dockree, S. J. Dodsworth, R. M. Durbin, A. Ellington, K. L. Evans, J. M. Fey, K. Fleming, L. French, A. A. Garner, J. G. R. Gilbert, M. E. Goward, D. Grafham, M. N. Griffiths, C. Hall, R. Hall, G. Hall-Tamlyn, R. W. Heathcott, S. Ho, S. Holmes, S. E. Hunt, M. C. Jones, J. Kershaw, A. Kimberley, A. King, G. K. Laird, C. F. Langford, M. A. Leversha, C. Lloyd, D. M. Lloyd, I. D. Martyn, M. Mashreghi-Mohammadi, L. Matthews, O. T. McCann, J. McClay, S. McLaren, A. A. McMurray, S. A. Milne, B. J. Mortimore, C. N. Odell, R. Pavitt, A. V. Pearce, D. Pearson, B. J. Phillimore, S. H. Phillips, R. W. Plumb, H. Ramsay, Y. Ramsey, L. Rogers, M. T. Ross, C. E. Scott, H. K. Sehra, C. D. Skuce, S. Smalley, M. L. Smith, C. Soderlund, L. Spragon, C. A. Steward, J. E. Sulston, R. M. Swann, M. Vaudin, M. Wall, J. M. Wallis, M. N. Whiteley, D. Willey, L. Williams, S. Williams, H. Williamson, T. E. Wilmer, L. Wilming, C. L. Wright, T. Hubbard, D. R. Bentley, S. Beck, J. Rogers, N. Shimizu, S. Minoshima, K. Kawasaki, T. Sasaki, S. Asakawa, J. Kudoh, A. Shintani, K. Shibuya, Y. Yoshizaki, N. Aoki, S. Mitsuyama, B. A. Roe, F. Chen, L. Chu, J. Crabtree, S. Deschamps, A. Do, T. Do, A. Dorman, F. Fang, Y. Fu, P. Hu, A. Hua, S. Kenton, H. Lai, H. I. Lao, J. Lewis, S. Lewis, S.-P. Lin, P. Loh, E. Malaj, Thanh Nguyen, H. Pan, S. Phan, S. Qi, Y. Qian, L. Ray, Q. Ren, S. Shaull, D. Sloan, L. Song, Q. Wang, Y. Wang, Z. Wang, J. White, D. Willingham, H. Wu, Z. Yao, M. Zhan, G. Zhang, S. Chissoe, J. Murray, N. Miller, P. Minx, R. Fulton, D. Johnson, G. Bemis, D. Bentley, H. Bradshaw, S. Bourne, M. Cordes, Z. Du, L. Fulton, D. Goela, T. Graves, J. Hawkins, K. Hinds, K. Kemp, P. Latreille, D. Layman, P. Ozersky, T. Rohlfing, P. Scheet, C. Walker, A. Wamsley, P. Wohldmann, K. Pepin, J. Nelson, I. Korf, J. A. Bedell, L. Hillier, E. Mardis, R. Waterston, R. Wilson, B. S. Emanuel, T. Shaikh, H. Kurahashi, S. Saitta, M. L. Budarf, H. E. McDermid, A. Johnson, A. C. C. Wong, B. E. Morrow, L. Edelmann, U. J. Kim, H. Shizuya, M. I. Simon, J. P. Dumanski, M. Peyrard, D. Kedra, E. Seroussi, I. Fransson, I. Tapia, C. E. Bruder and K. P. O'Brien
Additional contact information
I. Dunham: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. R. Hunt: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. E. Collins: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. Bruskiewich: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
D. M. Beare: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. Clamp: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. J. Smink: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. Ainscough: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. P. Almeida: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. Babbage: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Bagguley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. Bailey: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
K. Barlow: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
K. N. Bates: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
O. Beasley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. P. Bird: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. Blakey: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. M. Bridgeman: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
D. Buck: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
J. Burgess: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
W. D. Burrill: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. Burton: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Carder: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
N. P. Carter: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
Y. Chen: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
G. Clark: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. M. Clegg: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
V. Cobley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. G. Cole: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. E. Collier: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. E. Connor: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
D. Conroy: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
N. Corby: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
G. J. Coville: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. V. Cox: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. Davis: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
E. Dawson: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
P. D. Dhami: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Dockree: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. J. Dodsworth: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
R. M. Durbin: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. Ellington: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
K. L. Evans: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. M. Fey: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
K. Fleming: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. French: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. A. Garner: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. G. R. Gilbert: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
D. Grafham: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. N. Griffiths: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Hall: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
R. Hall: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
G. Hall-Tamlyn: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. W. Heathcott: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
S. Ho: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
S. Holmes: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. E. Hunt: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. C. Jones: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. Kershaw: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. Kimberley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. King: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
G. K. Laird: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. F. Langford: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. A. Leversha: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Lloyd: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
D. M. Lloyd: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
I. D. Martyn: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. Mashreghi-Mohammadi: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. Matthews: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
O. T. McCann: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. McClay: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. McLaren: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. A. McMurray: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. A. Milne: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
B. J. Mortimore: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. N. Odell: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. Pavitt: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
A. V. Pearce: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
D. Pearson: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
B. J. Phillimore: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. H. Phillips: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. W. Plumb: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
H. Ramsay: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
Y. Ramsey: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. Rogers: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. T. Ross: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. E. Scott: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
H. K. Sehra: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. D. Skuce: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. Smalley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. L. Smith: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. Soderlund: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. Spragon: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. A. Steward: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. E. Sulston: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
R. M. Swann: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. Vaudin: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
M. Wall: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. M. Wallis: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
M. N. Whiteley: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
D. Willey: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. Williams: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. Williams: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
H. Williamson: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
T. E. Wilmer: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
L. Wilming: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
C. L. Wright: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
T. Hubbard: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
D. R. Bentley: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
S. Beck: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
J. Rogers: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
N. Shimizu: Keio University School of Medicine
S. Minoshima: Keio University School of Medicine
K. Kawasaki: Keio University School of Medicine
T. Sasaki: Keio University School of Medicine
S. Asakawa: Keio University School of Medicine
J. Kudoh: Keio University School of Medicine
A. Shintani: Keio University School of Medicine
K. Shibuya: Keio University School of Medicine
Y. Yoshizaki: Keio University School of Medicine
N. Aoki: Keio University School of Medicine
S. Mitsuyama: Keio University School of Medicine
B. A. Roe: The University of Oklahoma
F. Chen: The University of Oklahoma
L. Chu: The University of Oklahoma
J. Crabtree: The University of Oklahoma
S. Deschamps: The University of Oklahoma
A. Do: The University of Oklahoma
T. Do: The University of Oklahoma
A. Dorman: The University of Oklahoma
F. Fang: The University of Oklahoma
Y. Fu: The Sanger Centre, Wellcome Trust Genome Campus, Hinxton
P. Hu: The University of Oklahoma
A. Hua: The University of Oklahoma
S. Kenton: The University of Oklahoma
H. Lai: The University of Oklahoma
H. I. Lao: The University of Oklahoma
J. Lewis: The University of Oklahoma
S. Lewis: The University of Oklahoma
S.-P. Lin: The University of Oklahoma
P. Loh: The University of Oklahoma
E. Malaj: The University of Oklahoma
H. Pan: The University of Oklahoma
S. Phan: The University of Oklahoma
S. Qi: The University of Oklahoma
Y. Qian: The University of Oklahoma
L. Ray: The University of Oklahoma
Q. Ren: The University of Oklahoma
S. Shaull: The University of Oklahoma
D. Sloan: The University of Oklahoma
L. Song: The University of Oklahoma
Q. Wang: The University of Oklahoma
Y. Wang: The University of Oklahoma
Z. Wang: The University of Oklahoma
J. White: The University of Oklahoma
D. Willingham: The University of Oklahoma
H. Wu: The University of Oklahoma
Z. Yao: The University of Oklahoma
M. Zhan: The University of Oklahoma
G. Zhang: The University of Oklahoma
S. Chissoe: Genome Sequencing Center, Washington University School of Medicine
J. Murray: Genome Sequencing Center, Washington University School of Medicine
N. Miller: Genome Sequencing Center, Washington University School of Medicine
P. Minx: Genome Sequencing Center, Washington University School of Medicine
R. Fulton: Genome Sequencing Center, Washington University School of Medicine
D. Johnson: Genome Sequencing Center, Washington University School of Medicine
G. Bemis: Genome Sequencing Center, Washington University School of Medicine
D. Bentley: Genome Sequencing Center, Washington University School of Medicine
H. Bradshaw: Genome Sequencing Center, Washington University School of Medicine
S. Bourne: Genome Sequencing Center, Washington University School of Medicine
M. Cordes: Genome Sequencing Center, Washington University School of Medicine
Z. Du: Genome Sequencing Center, Washington University School of Medicine
L. Fulton: Genome Sequencing Center, Washington University School of Medicine
D. Goela: Genome Sequencing Center, Washington University School of Medicine
T. Graves: Genome Sequencing Center, Washington University School of Medicine
J. Hawkins: Genome Sequencing Center, Washington University School of Medicine
K. Hinds: Genome Sequencing Center, Washington University School of Medicine
K. Kemp: Genome Sequencing Center, Washington University School of Medicine
P. Latreille: Genome Sequencing Center, Washington University School of Medicine
D. Layman: Genome Sequencing Center, Washington University School of Medicine
P. Ozersky: Genome Sequencing Center, Washington University School of Medicine
T. Rohlfing: Genome Sequencing Center, Washington University School of Medicine
P. Scheet: Genome Sequencing Center, Washington University School of Medicine
C. Walker: Genome Sequencing Center, Washington University School of Medicine
A. Wamsley: Genome Sequencing Center, Washington University School of Medicine
P. Wohldmann: Genome Sequencing Center, Washington University School of Medicine
K. Pepin: Genome Sequencing Center, Washington University School of Medicine
J. Nelson: Genome Sequencing Center, Washington University School of Medicine
I. Korf: Genome Sequencing Center, Washington University School of Medicine
J. A. Bedell: Genome Sequencing Center, Washington University School of Medicine
L. Hillier: Genome Sequencing Center, Washington University School of Medicine
E. Mardis: Genome Sequencing Center, Washington University School of Medicine
R. Waterston: Genome Sequencing Center, Washington University School of Medicine
R. Wilson: Genome Sequencing Center, Washington University School of Medicine
B. S. Emanuel: University of Pennsylvania School of Medicine
T. Shaikh: University of Pennsylvania School of Medicine
H. Kurahashi: University of Pennsylvania School of Medicine
S. Saitta: University of Pennsylvania School of Medicine
M. L. Budarf: University of Alberta
H. E. McDermid: University of Alberta
A. Johnson: University of Alberta
A. C. C. Wong: University of Alberta
B. E. Morrow: Albert Einstein College of Medicine
L. Edelmann: Albert Einstein College of Medicine
U. J. Kim: California Institute of Technology
H. Shizuya: California Institute of Technology
M. I. Simon: California Institute of Technology
J. P. Dumanski: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
M. Peyrard: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
D. Kedra: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
E. Seroussi: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
I. Fransson: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
I. Tapia: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
C. E. Bruder: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00
K. P. O'Brien: Clinical Genetics Unit, Karolinska Hospital, CMM bldg. L8:00

Nature, 1999, vol. 402, issue 6761, 489-495

Abstract: Abstract Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those without known function, their control elements, and, by inference, the proteins they encode, as well as all other biologically important sequences. Furthermore, the sequence is a rich and permanent source of information for the design of further biological studies of the organism and for the study of evolution through cross-species sequence comparison. The power of this approach has been amply demonstrated by the determination of the sequences of a number of microbial and model organisms. The next step is to obtain the complete sequence of the entire human genome. Here we report the sequence of the euchromatic part of human chromosome 22. The sequence obtained consists of 12 contiguous segments spanning 33.4 megabases, contains at least 545 genes and 134 pseudogenes, and provides the first view of the complex chromosomal landscapes that will be found in the rest of the genome.

Date: 1999
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DOI: 10.1038/990031

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