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How to spot a protein in a crowd

Alison Abbott

Nature, 1999, vol. 402, issue 6763, 716-717

Abstract: The two key steps in classical proteomics are the separation of proteins in a sample derived from cells or tissues, and their subsequent identification. The best separation method is 2D gel electrophoresis, in which spots of a carefully prepared mixture of proteins extracted from cells or tissues are applied to a polyacrylamide gel.

Date: 1999
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DOI: 10.1038/45356

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