Telomeric tethers

Wai-Hong Tham () and Virginia A. Zakian ()
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Wai-Hong Tham: Princeton University
Virginia A. Zakian: Princeton University

Nature, 2000, vol. 403, issue 6765, 34-35

Abstract: Eukaryotic chromosomes are confined to the nucleus, which is separated from the rest of the cell by a membrane called the nuclear envelope. Within this envelope are protein-lined channels known as nuclear-pore complexes, through which cellular material is transported into and out of the nucleus. A study now links this to chromosomes, showing that the three-dimensional organization of chromosomes is provided, in part, by interactions with the nuclear pore complex.

Date: 2000
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DOI: 10.1038/47385

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