Protamine wars

Andrew G. Clark () and Alberto Civetta
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Andrew G. Clark: Institute of Molecular Evolutionary Genetics, Pennsylvania State University
Alberto Civetta: Institute of Molecular Evolutionary Genetics, Pennsylvania State University

Nature, 2000, vol. 403, issue 6767, 261-263

Abstract: Proteins that evolve much more quickly than normal are of interest because the rapid changes may give us clues as to their function. Rapid evolution of male reproductive genes has now been directly demonstrated in primates — specifically, in the genes encoding proteins called protamines, which are essential for male fertility. However, this accelerated evolution is not necessarily a sign of positive Darwinian selection.

Date: 2000
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DOI: 10.1038/35002236

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