A predictor of pathology

John C. Rothwell ()
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John C. Rothwell: MRC HMBU, Institute of Neurology, Queen Square

Nature, 2000, vol. 403, issue 6769, 495-496

Abstract: Most slowly progressive neurodegenerative diseases begin long before clinical symptoms appear, making it difficult to predict who will succumb to them. Some genetic tests are available, but the first behavioural indicator of disease has now been identified for one neurodegenerative disorder, Huntington's disease. People who carry the affected gene but do not yet show symptoms have an impaired ability to point accurately at targets up to seven years before symptoms begin.

Date: 2000
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DOI: 10.1038/35000692

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