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A new model for protein stereospecificity

Andrew D. Mesecar and Daniel E. Koshland ()
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Andrew D. Mesecar: Center for Pharmaceutical Biotechnology, University of Illinois at Chicago
Daniel E. Koshland: Center for Pharmaceutical Biotechnology, University of Illinois at Chicago

Nature, 2000, vol. 403, issue 6770, 614-615

Abstract: Abstract The ability of proteins to discriminate between optical isomers is vital for living systems and is exploited in drug design. Here we present a new model to explain this stereospecificity of proteins on the basis of crystallographic data.

Date: 2000
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DOI: 10.1038/35001144

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