Which way is up?

Mark Peifer () and Ulrich Tepass ()
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Mark Peifer: University of North Carolina at Chapel Hill
Ulrich Tepass: University of Toronto

Nature, 2000, vol. 403, issue 6770, 611-612

Abstract: Houses have roofs and foundations which are built of different materials and require upkeep. Likewise, cells — especially for instance those that form an epithelial sheet — have a top and bottom, and the right proteins have to be directed to the right place throughout the cells' lives. A molecule called Scribble now emerges as a central player in the maintenance of cell polarity in the fruitflyDrosophila.

Date: 2000
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DOI: 10.1038/35001187

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