p53 sends nucleotides to repair DNA

Guillermina Lozano () and Stephen J. Elledge ()
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Guillermina Lozano: University of Texas, M. D. Anderson Cancer Center
Stephen J. Elledge: Baylor College of Medicine

Nature, 2000, vol. 404, issue 6773, 24-25

Abstract: Mutations in the p53 protein or components of the pathway that regulates it are one of the main causes of cancer – normally, p53 prevents cells that have been damaged from contributing to tumour formation. Now another function of p53 emerges. It seems that the protein also participates in the process of DNA repair itself.

Date: 2000
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DOI: 10.1038/35003670

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