Reeling CASK into the nucleus

David S. Bredt ()
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David S. Bredt: Department of Physiology University of California at San Francisco School of Medicine

Nature, 2000, vol. 404, issue 6775, 241-242

Abstract: Cells send messages to their neighbours through ‘junctional complexes’, which link molecules on the cell surface to the cytoskeleton beneath. One of the proteins that forms these complexes, CASK, is now shown to travel from the cell surface to the nucleus, where it regulates gene expression by binding to DNA.

Date: 2000
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DOI: 10.1038/35005208

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