A unique circadian-rhythm photoreceptor

Patrick Emery, Ralf Stanewsky, Jeffrey C. Hall and Michael Rosbash ()
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Patrick Emery: NSF Center for Biological Timing, Brandeis University
Ralf Stanewsky: Zoologisches Institut, Universität Regensburg
Jeffrey C. Hall: NSF Center for Biological Timing, Brandeis University
Michael Rosbash: NSF Center for Biological Timing, Brandeis University

Nature, 2000, vol. 404, issue 6777, 456-457

Abstract: Abstract Cryptochrome proteins are critical for circadian rhythms, but their function(s) is uncertain. Here we show that a mutation in a cryptochrome (dCRY) from the fruitfly Drosophila blocks an essential photoresponse of circadian rhythms, namely arrhythmicity under constant light conditions. We conclude that dCRY acts as a key photoreceptor for circadian rhythms and that there is probably no other comparable photoreceptor in this species.

Date: 2000
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DOI: 10.1038/35006558

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