Decoy receptors thwart B cells

Carl F. Ware ()
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Carl F. Ware: Division of Molecular Immunology La Jolla Institute for Allergy and Immunology

Nature, 2000, vol. 404, issue 6781, 949-950

Abstract: Lupus erythematosus is a debilitating autoimmune disease, a feature of which is the presence of hyperactive B cells. The discovery of a new pathway that stimulates B-cell proliferation provides insight into the biology of this disease, and allowed the construction of antagonists of the pathway that halt disease progression in mice.

Date: 2000
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DOI: 10.1038/35010263

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