One-hit neuronal death

Nathaniel Heintz ()
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Nathaniel Heintz: Laboratory of Molecular Biology, Howard Hughes Medical Institute, Rockefeller University

Nature, 2000, vol. 406, issue 6792, 137-139

Abstract: Statistical analyses of neuronal death rates in a variety of neurodegenerative disorders indicate that a 'one-hit' model of cell death may be common to all of them. In this model, affected neurons are in an abnormal state in which there is a higher chance that a rare catastrophic event will lead to cell death.

Date: 2000
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DOI: 10.1038/35018196

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