Hepatocytes from non-hepatic adult stem cells

Malcolm R. Alison (), Richard Poulsom, Rosemary Jeffery, Amar P. Dhillon, Alberto Quaglia, Joe Jacob, Marco Novelli, Grant Prentice, Jill Williamson and Nicholas A. Wright
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Malcolm R. Alison: Imperial College School of Medicine, Hammersmith Campus
Richard Poulsom: Histopathology Unit, Imperial Cancer Research Fund
Rosemary Jeffery: Histopathology Unit, Imperial Cancer Research Fund
Amar P. Dhillon: Royal Free Campus, Royal Free and University College School of Medicine
Alberto Quaglia: Royal Free Campus, Royal Free and University College School of Medicine
Joe Jacob: Imperial College School of Medicine, Hammersmith Campus
Marco Novelli: University College London
Grant Prentice: Royal Free Campus, Royal Free and University College School of Medicine
Jill Williamson: Human Cytogenetics Laboratory, Imperial Cancer Research Fund
Nicholas A. Wright: Imperial College School of Medicine, Hammersmith Campus

Nature, 2000, vol. 406, issue 6793, 257-257

Abstract: Abstract Stem cells are undifferentiated long-lived cells that are capable of many rounds of division. Here we show that adult human liver cells can be derived from stem cells originating in the bone marrow or circulating outside the liver, raising the possibility that blood-system stem cells could be used clinically to generate hepatocytes for replacing damaged tissue.

Date: 2000
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DOI: 10.1038/35018642

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