Molecular switches in metastasis

Anne Ridley ()
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Anne Ridley: Ludwig Institute for Cancer Research, University College London

Nature, 2000, vol. 406, issue 6795, 466-467

Abstract: DNA microarrays have been used to analyse the gene-expression profiles of a variety of cancers. Now this technique has revealed several genes that are upregulated specifically in metastatic melanomas compared with their non-metastatic counterparts. One of these genes, RhoC, can induce metastasis all by itself.

Date: 2000
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DOI: 10.1038/35020170

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