Benefits of bad telomeres

Douglas Hanahan ()
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Douglas Hanahan: Hormone Research Institute, and the Comprehensive Cancer Center University of California at San Francisco

Nature, 2000, vol. 406, issue 6796, 573-574

Abstract: The enzyme telomerase is activated in most human cancers. So it comes as a surprise to learn that mice engineered to lack telomerase, as well as a tumour-suppressor protein, p53, develop cancers that would not appear in mice lacking just p53. The explanation may lie in the nature of cancer development.

Date: 2000
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DOI: 10.1038/35020662

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