Caffeine synthase gene from tea leaves

Misako Kato, Kouichi Mizuno, Alan Crozier (), Tatsuhito Fujimura and Hiroshi Ashihara
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Misako Kato: Faculty of Science, Ochanomizu University
Kouichi Mizuno: Institute of Agricultural and Forest Engineering, University of Tsukuba
Alan Crozier: Plant Products and Human Nutrition Group, Institute of Biomedical and Life Sciences, University of Glasgow
Tatsuhito Fujimura: Institute of Agricultural and Forest Engineering, University of Tsukuba
Hiroshi Ashihara: Faculty of Science, Ochanomizu University

Nature, 2000, vol. 406, issue 6799, 956-957

Abstract: Abstract Caffeine synthase is an enzyme that catalyses the final two steps in the caffeine biosynthesis pathway. We have cloned the gene encoding caffeine synthase from young leaves of tea (Camellia sinensis), opening up the possibility of creating tea and coffee (Coffea arabica) plants that are naturally deficient in caffeine. Consumers concerned about the possible adverse effects of caffeine consumption will welcome this development towards caffeine-free drinks that retain their flavour.

Date: 2000
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DOI: 10.1038/35023072

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