Sheep, lilies and human genetics

Allen E. Bale ()
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Allen E. Bale: Yale University School of Medicine

Nature, 2000, vol. 406, issue 6799, 944-945

Abstract: Studies of an epidemic of sheep cyclopia in the western United States have led to a possible treatment for human skin cancer. The compound that caused the cyclopia inhibits the Hedgehog cellular signalling pathway, which is activated in most basal-cell carcinomas.

Date: 2000
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DOI: 10.1038/35023197

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