RNA editing meets DNA shuffling

Ming Tian and Frederick W. Alt ()
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Ming Tian: Howard Hughes Medical Institute, The Childrens' Hospital and Center for Blood Research
Frederick W. Alt: Howard Hughes Medical Institute, The Childrens' Hospital and Center for Blood Research

Nature, 2000, vol. 407, issue 6800, 31-33

Abstract: The immune system can tailor its production of antibodies to the type of infection. Three sequential DNA-shuffling processes underlie this ability. The same protein is responsible for the last two of the processes, and oddly it is an RNA-editing rather than a DNA-recombining enzyme.

Date: 2000
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DOI: 10.1038/35024189

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