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KSHV-like herpesviruses in chimps and gorillas

Vincent Lacoste, Philippe Mauclre, Guy Dubreuil, John Lewis, Marie-Claude Georges-Courbot and Antoine Gessain ()
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Vincent Lacoste: Institut Pasteur
Philippe Mauclre: Institut Pasteur
Guy Dubreuil: Centre International de Recherches Médicales
John Lewis: International Zoo Veterinary group
Marie-Claude Georges-Courbot: Centre International de Recherches Médicales
Antoine Gessain: Institut Pasteur

Nature, 2000, vol. 407, issue 6801, 151-152

Abstract: Abstract Among the herpesviruses1, KSHV (Kaposi's-sarcoma-associated herpesvirus) is the human prototype of the rhadinovirus genus2. Rhadinoviruses (or γ2-herpesviruses) are found in several animal species, including New and Old World monkeys, but not in the great apes3,4,5. Here we describe the detection and sequencing of a polymerase gene fragment from three new rhadinoviruses discovered in chimpanzees and in a gorilla, which are more closely related to KSHV than to any other virus of this genus described so far. Our results indicate that the great apes from central Africa could provide a reservoir of new γ2-herpesviruses that are potentially transmissible to humans.

Date: 2000
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DOI: 10.1038/35025145

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