Surfing the p53 network

Bert Vogelstein (), David Lane () and Arnold J. Levine ()
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Bert Vogelstein: The Howard Hughes Medical Institute and Johns Hopkins Oncology Center
David Lane: Ninewells Hospital, University of Dundee
Arnold J. Levine: Laboratory of Cancer Biology, Genetics, and Molecular Biophysics, Rockefeller University

Nature, 2000, vol. 408, issue 6810, 307-310

Abstract: The p53 tumour-suppressor gene integrates numerous signals that control cell life and death. As when a highly connected node in the Internet breaks down, the disruption of p53 has severe consequences.

Date: 2000
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DOI: 10.1038/35042675

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