Industrial biocatalysis today and tomorrow

A. Schmid, J. S. Dordick (), B. Hauer (), A. Kiener (), M. Wubbolts () and B. Witholt ()
Additional contact information
A. Schmid: Institute of Biotechnology, ETH-Hönggerberg
J. S. Dordick: Department of Chemical Engineering Rensselaer Polytechnic Institute
B. Hauer: BASF AG
A. Kiener: Lonza Biotechnology R&D
M. Wubbolts: DSM Biotech GmbH
B. Witholt: Institute of Biotechnology, ETH-Hönggerberg

Nature, 2001, vol. 409, issue 6817, 258-268

Abstract: Abstract The use of biocatalysis for industrial synthetic chemistry is on the verge of significant growth. Biocatalytic processes can now be carried out in organic solvents as well as aqueous environments, so that apolar organic compounds as well as water-soluble compounds can be modified selectively and efficiently with enzymes and biocatalytically active cells. As the use of biocatalysis for industrial chemical synthesis becomes easier, several chemical companies have begun to increase significantly the number and sophistication of the biocatalytic processes used in their synthesis operations.

Date: 2001
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DOI: 10.1038/35051736

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