Mining the draft human genome

Ewan Birney (), Alex Bateman, Michele E. Clamp and Tim J. Hubbard
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Ewan Birney: The European Bioinformatics Institute, Wellcome Trust Genome Campus
Alex Bateman: The Sanger Centre, Wellcome Trust Genome Campus
Michele E. Clamp: The Sanger Centre, Wellcome Trust Genome Campus
Tim J. Hubbard: The Sanger Centre, Wellcome Trust Genome Campus

Nature, 2001, vol. 409, issue 6822, 827-828

Abstract: Abstract Now that the draft human genome sequence is available, everyone wants to be able to use it. However, we have perhaps become complacent about our ability to turn new genomes into lists of genes. The higher volume of data associated with a larger genome is accompanied by a much greater increase in complexity. We need to appreciate both the scale of the challenge of vertebrate genome analysis and the limitations of current gene prediction methods and understanding.

Date: 2001
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DOI: 10.1038/35057004

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