Evolutionary analyses of the human genome

Wen-Hsiung Li (), Zhenglong Gu, Haidong Wang and Anton Nekrutenko
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Wen-Hsiung Li: Ecology and Evolution, University of Chicago
Zhenglong Gu: Ecology and Evolution, University of Chicago
Haidong Wang: Ecology and Evolution, University of Chicago
Anton Nekrutenko: Ecology and Evolution, University of Chicago

Nature, 2001, vol. 409, issue 6822, 847-849

Abstract: Abstract The completion of the human genome will greatly accelerate the development of a new branch of science—evolutionary genomics. We can now directly address important questions about the evolutionary history of human genes and their regulatory sequences. Computational analyses of the human genome will reveal the number of genes and repetitive elements, the extent of gene duplication and compositional heterogeneity in the human genome, and the extent of domain shuffling and domain sharing among proteins. Here we present some first glimpses of these features.

Date: 2001
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DOI: 10.1038/35057039

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