Identification of CRE1 as a cytokinin receptor from Arabidopsis

Tsutomu Inoue, Masayuki Higuchi, Yukari Hashimoto, Motoaki Seki, Masatomo Kobayashi, Tomohiko Kato, Satoshi Tabata, Kazuo Shinozaki and Tatsuo Kakimoto ()
Additional contact information
Tsutomu Inoue: Graduate School of Science, Osaka University,Toyonaka
Masayuki Higuchi: Graduate School of Science, Osaka University,Toyonaka
Yukari Hashimoto: Graduate School of Science, Osaka University,Toyonaka
Motoaki Seki: Laboratory of Plant Molecular Biology, RIKEN Tsukuba Institute
Masatomo Kobayashi: Laboratory of Plant Molecular Biology, RIKEN Tsukuba Institute
Tomohiko Kato: Kazusa DNA Research Institute, Kisarazu
Satoshi Tabata: Kazusa DNA Research Institute, Kisarazu
Kazuo Shinozaki: Laboratory of Plant Molecular Biology, RIKEN Tsukuba Institute
Tatsuo Kakimoto: Graduate School of Science, Osaka University,Toyonaka

Nature, 2001, vol. 409, issue 6823, 1060-1063

Abstract: Abstract Cytokinins are a class of plant hormones that are central to the regulation of cell division and differentiation in plants1,2. It has been proposed that they are detected by a two-component system, because overexpression of the histidine kinase gene CKI1 induces typical cytokinin responses3 and genes for a set of response regulators of two-component systems can be induced by cytokinins4,5. Two-component systems use a histidine kinase as an environmental sensor and rely on a phosphorelay for signal transduction. They are common in microorganisms, and are also emerging as important signal detection routes in plants6,7,8,9. Here we report the identification of a cytokinin receptor. We identified Arabidopsis cre1 (cytokinin response 1) mutants, which exhibited reduced responses to cytokinins. The mutated gene CRE1 encodes a histidine kinase. CRE1 expression conferred a cytokinin-dependent growth phenotype on a yeast mutant that lacked the endogenous histidine kinase SLN1 (ref. 10), providing direct evidence that CRE1 is a cytokinin receptor. We also provide evidence that cytokinins can activate CRE1 to initiate phosphorelay signalling.

Date: 2001
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/35059117 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:409:y:2001:i:6823:d:10.1038_35059117

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/35059117

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().