Phylogeny and the origin of HIV-1

Andrew Rambaut, David L. Robertson, Oliver G. Pybus, Martine Peeters and Edward C. Holmes ()
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Andrew Rambaut: University of Oxford
David L. Robertson: University of Oxford
Oliver G. Pybus: University of Oxford
Martine Peeters: Laboratoire Retrovirus, IRD
Edward C. Holmes: University of Oxford

Nature, 2001, vol. 410, issue 6832, 1047-1048

Abstract: Abstract The origin of human immunodeficiency virus type 1 (HIV-1) is controversial. We show here that viruses obtained from the Democratic Republic of Congo in Africa have a quantitatively different phylogenetic tree structure from those sampled in other parts of the world. This indicates that the structure of HIV-1 phylogenies is the result of epidemiological processes acting within human populations alone, and is not due to multiple cross-species transmission initiated by oral polio vaccination.

Date: 2001
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DOI: 10.1038/35074179

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