Haematopoietic cell transplantation as immunotherapy

Frederick R. Appelbaum
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Frederick R. Appelbaum: Fred Hutchinson Cancer Research Center

Nature, 2001, vol. 411, issue 6835, 385-389

Abstract: Abstract The graft-versus-tumour effect seen after allogeneic (genetically different) haematopoietic cell transplantation for human malignancies represents the clearest example of the power of the human immune system to eradicate cancer. Recent advances in our understanding of the immunobiology of stem-cell engraftment, tolerance and tumour eradication are allowing clinicians to better harness this powerful effect.

Date: 2001
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DOI: 10.1038/35077251

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