Genes lost during evolution

Jeroen Roelofs and Peter J. M. Van Haastert ()
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Jeroen Roelofs: University of Groningen
Peter J. M. Van Haastert: University of Groningen

Nature, 2001, vol. 411, issue 6841, 1013-1014

Abstract: Abstract One of the main conclusions presented by the International Human Genome Sequencing Consortium is that “hundreds of genes appear to have resulted from horizontal gene transfer from bacteria at some point in the vertebrate lineage”1. We noticed that a significant proportion of these human genes have closely related orthologues in the primitive eukaryote Dictyostelium. This observation supports independent gene loss in multiple lineages (worm, fly, yeast, plants) rather than horizontal gene transfer from bacteria.

Date: 2001
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DOI: 10.1038/35082627

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