Stem cells in tissue engineering

Paolo Bianco () and Pamela Gehron Robey ()
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Paolo Bianco: Universita 'La Sapienza'
Pamela Gehron Robey: Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health

Nature, 2001, vol. 414, issue 6859, 118-121

Abstract: Abstract The concept of producing 'spare parts' of the body for replacement of damaged or lost organs lies at the core of the varied biotechnological practices referred to generally as tissue engineering. Use of postnatal stem cells has the potential to significantly alter the perspective of tissue engineering. Successful long-term restoration of continuously self-renewing tissues such as skin, for example, depends on the use of extensively self-renewing stem cells. The identification and isolation of stem cells from a number of tissues provides appropriate targets for prospective gene therapies.

Date: 2001
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DOI: 10.1038/35102181

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