Peptide antibiotics in mast cells of fish

Umaporn Silphaduang and Edward J. Noga ()
Additional contact information
Umaporn Silphaduang: College of Veterinary Medicine, North Carolina State University
Edward J. Noga: College of Veterinary Medicine, North Carolina State University

Nature, 2001, vol. 414, issue 6861, 268-269

Abstract: Abstract Antimicrobial peptides are increasingly recognized as a critical first line of defence against many pathogens and have been isolated from epithelial tissues and blood cells of many vertebrates, as well as from prokaryotes, plants and invertebrates1,2. Here we show that 'piscidins', a previously undiscovered family of peptide antibiotics isolated from fish, reside in mast cells, an immune cell of uncertain function that is present in all vertebrate classes3,4. Until now, no peptide antibiotic has been isolated from the mast cells of any animal, and our discovery indicates that these cells may be critical in fighting many infectious diseases.

Date: 2001
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/35104690 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:414:y:2001:i:6861:d:10.1038_35104690

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/35104690

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().