Hedgehog crosses the snail's midline

Alexander J. Nederbragt (), André E. van Loon and Wim J. A. G. Dictus
Additional contact information
Alexander J. Nederbragt: Utrecht University
André E. van Loon: Utrecht University
Wim J. A. G. Dictus: Utrecht University

Nature, 2002, vol. 417, issue 6891, 811-812

Abstract: Abstract According to the dorsoventral axis-inversion theory1, protostomes (such as insects, snails and worms) are organized upside-down by comparison with deuterostomes (vertebrates)2,3,4,5, in which case their respective ventrally (belly-side) and dorsally (back-side) located nervous systems, as well as their midline regions, should all be derived from a common ancestor5. Here we provide experimental evidence for such homology by showing that an orthologue of hedgehog, an important gene in midline patterning in vertebrates, is expressed along the belly of the larva of the limpet Patella vulgata. This finding supports the existence of a similar mechanism for the development of the midline of the nervous system in protostomes and deuterostomes.

Date: 2002
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/417811b Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:417:y:2002:i:6891:d:10.1038_417811b

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/417811b

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().